SIP-ing the Elixir of Youth

نویسندگان

  • William Mair
  • Kristan K. Steffen
  • Andrew Dillin
چکیده

AMP-activated protein kinase (AMPK) is a conserved cellular fuel gauge previously implicated in aging. In this issue, Lu et al. (2011) describe how age-related deacetylation of Sip2, a subunit of the AMPK homolog in yeast, acts as a life span clock that can be wound backward or forward to modulate longevity.

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عنوان ژورنال:
  • Cell

دوره 146  شماره 

صفحات  -

تاریخ انتشار 2011